Guided course / Microbiology
How a bacterium survives
Follow one representative bacterium through a changing environment. The route responds to visible evidence rules; bacterial mechanisms vary among species.
- 6 connected chapters
- 15–20 minutes
- No account
- Saved only on this device
Chapter 1 of 6 · Activity 1 of 13
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Hold the boundary
The cell membrane controls molecular passage; the cell wall primarily resists mechanical and osmotic stress. Small nonpolar oxygen crosses the lipid bilayer more readily than glucose or a charged sodium ion.
Representative answer and reasoning
Choose oxygen. Glucose is large and polar, while sodium is charged, so both usually depend on membrane proteins.
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Move matter
Diffusion describes net movement from higher concentration to lower concentration. Channels and carriers give selected substances paths through the membrane.
Representative answer and reasoning
Oxygen can cross directly; an ion can use a channel; a polar nutrient can use a selective carrier.
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Survive salt shock
In osmosis, water moves both ways while the net movement follows relative water availability. A saltier exterior produces net water loss; a dilute exterior produces net water entry and the wall helps resist expansion.
Representative answer and reasoning
After external salt rises, predict net water movement out of the bacterium.
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Pay for movement
Down-gradient transport can be passive. Accumulating a scarce nutrient against its gradient requires an energy-coupled process, though the transporter need not use ATP directly.
Representative answer and reasoning
Choose an energy-coupled transporter when the cell must keep accumulating a nutrient already concentrated inside.
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Build a response
DNA stores an instruction, RNA carries an expressed message, and a ribosome reads the message while assembling a protein. This useful model leaves out more complex regulation.
Representative answer and reasoning
Order the pathway DNA → RNA → ribosome → protein.
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Face an antibiotic
Simplified antibiotic targets include cell-wall assembly, membrane integrity, and ribosome function. A ribosome-targeting mechanism disrupts normal production of a new transport protein. This is not treatment guidance.
Representative answer and reasoning
Connect wall disruption to structural support, membrane disruption to controlled gradients, and ribosome disruption to protein production.
How the route responds
Strong evidence can reveal an optional extension. Developing evidence schedules delayed retrieval. Two unsuccessful attempts or a high-confidence mismatch makes support recommended. Every branch is visible, explained, and skippable.
The readable pack behind the route
pack.json- Identity, version, license, and capabilities.
catalog.json- Concepts and their relationships.
courses.json- The required spine and optional branches.
items.json- Prompts, responses, evaluation, and feedback.
Scientific references
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